Conjunctival Fibrosarcoma: An Unusual Case with Inmunohistochemical Study

Keywords: Infant fibrosarcoma, conjunctive, immunohistochemistry, KI-67 antigen

Abstract

Fibrosarcomas are rare, malignant fibroblast tumors. The age range for children is between 5 and 10 years old. It affects deep soft tissues in the lower extremities or trunk and may present with rapid and variable growth. Objective: A case of conjunctival fibrosarcoma is presented. Clinical case: Male patient 10 years old. Evaluated in ophthalmology consultation by volume increase in bulbar region of the lower eyelid of the right eye, a week of evolution and rapid growth. Lesion approximately 1.5 x 1.2 cm hardened and with conjunctival hyperemia. Results: Tumor resection was performed, measures 3.5 x 2.3 cm, external surface yellowish-white and dark brown spotlight. Biopsy and immunohistochemistry are processed, reporting KI-67 antigen in 60% reflecting proliferative tissue activity. Conclusion: Well-differentiated conjunctival fibrosarcoma with high mitotic activity. It is referred for oncological treatment with ophthalmology follow up.

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Author Biographies

Nelson Sanguinetty, Universidad del Zulia. Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo y Facultad de Medicina, Universidad del Zulia. Maracaibo –
Venezuela.

Alexander Rabinovich, Universidad del Zulia. Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo y Facultad de Medicina, Universidad del Zulia. Maracaibo –
Venezuela.

María Martínez, Universidad del Zulia. Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo y Facultad de Medicina, Universidad del Zulia. Maracaibo –
Venezuela.

Emma Hernández, Hospital Universitario de Maracaibo, Venezuela.

Servicio de Oncología Pediátrica Hospital Universitario de Maracaibo - Venezuela.

Marielys Matos, Hospital Universitario de Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo -Venezuela.

Nadim El Maaz, Hospital Universitario de Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo -Venezuela.

Raúl Rabinovich, Hospital Universitario de Maracaibo, Venezuela.

Servicio de Oftalmología, Hospital Universitario de Maracaibo -Venezuela.

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Published
2023-05-02
How to Cite
Sanguinetty, N., Rabinovich, A., Martínez, M., Hernández, E., Matos, M., El Maaz, N., & Rabinovich, R. (2023). Conjunctival Fibrosarcoma: An Unusual Case with Inmunohistochemical Study. Journal of the University of Zulia , 14(40), 269-279. https://doi.org/10.46925//rdluz.40.15