Effect of IGF-1 and LEP/ob SNPs on growth parameters of Blanco Orejinegro cattle
Keywords:
creole bovine, molecular markers, precocity, productivity, zoogenetic resource
Abstract
The aim of this work was to identify the effect of some SNPs of the IGF-1 and LEP/ob genes, on the growth in animals of the Blanco Orejinegro creole breed (BON) and to evaluate the relationship of age at first calving (AFC) with the curve trajectory. For this, 1217 phenotypic and 439 genomic records of pure BON bovines were used. The Gompertz, Logistic, Von Bertalanffy and Brody models were evaluated. The individual growth curve parameters were estimated and the effect of SNPs of the IGF-1 and LEP/ob genes on the curve parameters was estimated through a linear model. Finally, the association of the curve parameters and the AFC was analyzed trough a linear model. The model that represented the best fit to the growth trajectory was Brody's. On average, the BON animals presented an adult weight (β0) of 479.9±7.4 kg and a growth rate expressing the daily weight gain as a proportion of the total weight (β2) of 0.002±0.00004. The SNPs rs110654613 (nucleotide change A/G) and rs110959643 (A/G), within the IGF-1 gene, showed a significant effect (p<0.05) on the parameters of the BON cattle growth curve. There were no associations of LEP/ob gene SNPs on the parameters of the BON cattle growth curve. AFC was significantly associated (p<0.05) with the parameters β0 and β2. It is concluded that the use of genomic information for the IGF-1 gene can lead to higher growth rates and earlier.
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References
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Gaviolli, V. R. N., Buzanskas, M. E., Cruz, V. A. R., Savegnago, R. P., Munari, D. P., Freitas, A. R., & Alencar, M. M. (2012). Genetic associations between weight at maturity and maturation rate with ages and weights at first and second calving in Canchim beef cattle. Journal of Applied Genetics, 53(3), 331–335. https://doi.org/10.1007/s13353-012-0100-6
Gompertz, B. (1825). On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life Contingencies. Philosophical Transactions ofthe Royal Society of London, 115, 513–583.
http://www.jstor.org/journals/rsl.html
Gui, L., Wang, Z., Jia, J., Zhang, C., Chen, Y., & Hou, S. (2018). IGF-1 Gen Polimorfizmi Çin Qinchuan Sığırında Büyüme Özelliklerini Etkiler. Kafkas Universitesi Veteriner Fakultesi Dergisi, 24(3), 387–392. https://doi.org/10.9775/kvfd.2017.19036
Hojjati, F., & Hossein-Zadeh, N. G. (2018). Comparison of non-linear growth models to describe the growth curve of Mehraban sheep. Journal of Applied Animal Research, 46(1), 499–504. https://doi.org/10.1080/09712119.2017.1348949
Inoue, K., Hosono, M., Oyama, H., & Hirooka, H. (2020). Genetic associations between reproductive traits for first calving and growth curve characteristics of Japanese Black cattle. Animal Science Journal, 91(1), 1–8. https://doi.org/10.1111/asj.13467
Lenth, R. V. (2016). Least-Squares Means: The R Package lsmeans. Journal of Statistical Software, 69(1), 1–33. https://doi.org/10.18637/jss.v069.i01
López-Herrera, A., Saldarriaga, O. A., Arango, A. E., Fabio, N., Olivera, M., Bedoya, G., y Ossa, J. E. (2001). Ganado Blanco Orejinegro (BON): Una alternativa para la producción en Colombia. Revista Colombiana de Ciencias Pecuarias, 14(2), 121–128. https://doi.org/10.17533/udea.rccp
Londoño-Gil, M., Rincón Flórez, J. C., Lopez-Herrera, A., y Gonzalez-Herrera, L. G. (2021). Genome-wide association study for growth traits in Blanco Orejinero (BON) cattle from Colombia. Livestock Science, 243(104366), 104366. https://doi.org/10.1016/j.livsci.2020.104366
Lusk, J. L. (2007). Association of single nucleotide polymorphisms in the leptin gene with body weight and backfat growth curve parameters for beef cattle 1. American Society of Animal Science, 85, 1865–1872. https://doi.org/10.2527/jas.2006-665
M-Rocha, J. F., Gallego, J. L., Vásquez, R. F., Pedraza, J. A., Echeverri, J., Cerón-Muñoz, M. F., y Martínez, R. (2012). Estimación de parámetros genéticos para edad al primer parto e intervalo entre partos en poblaciones bovinas de la raza Blanco Orejinegro (BON) en Colombia. Revista Colombiana de Ciencias Pecuarias, 25, 220–228. https://doi.org/10.17533/udea.rccp
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Rincón, J., y Quintero, J. (2015). Comparación de modelos no lineales para describir el crecimiento en ganado Blanco Orejinegro (BON). Revista CES Medicina Veterinaria y Zootecnia, 10(1), 31–37. https://doi.org/10.21615/cesmvz
Rogberg-Muñoz, A., Melucci, L., Prando, A., Villegas-Castagnasso, E. E., Ripoli, M. V., Peral-García, P., Baldo, A., Añon, M. C., & Giovambattista, G. (2011). Association of bovine chromosome 5 markers with birth and weaning weight in Hereford cattle raised under extensive conditions. Livestock Science, 135(2–3), 124–130. https://doi.org/10.1016/j.livsci.2010.06.160
Rogberg-Muñoz, A., Cantet, R. J. C., Elena, M., Pedro, J., Prando, A., Nélida, A., Verónica, M., y Giovambattista, G. (2013). Longitudinal analysis of the effects of IGF1 - SnaBI genotypes on the growth curve of Angus bull calves. Livestock Science, 154(1–3), 55–59. https://doi.org/10.1016/j.livsci.2013.03.016
Saleem, A. H. (2015). Role of Leptin in Growth, Reproduction and Milk Production in Farm Animals: A Review. Advances in Animal and Veterinary Sciences, 3(5), 302–307. https://doi.org/10.14737/journal.aavs/2015/3.5.302.307
Verhulst, P. (1838). Notice sur la loi que la population pursuit dans son accroissement. Correspondance Mathématique et Physique, 10,113-121. http://www.neo-classical-physics.info/uploads/3/4/3/6/34363841/verhulst_-_law_of_population.pdf
Von Bertalanffy, L. (1938). A quantitative theory of organic growth (inquires on growth laws. Human Biology, 10(2), 181–213. https://doi.org/10.2307/41447359
Andrade, P. C., Grossi, D. A., Paz, C. C. P., Alencar, M. M., Regitano, L. C. A., & Munari, D. P. (2008). Association of an insulin-like growth factor 1 gene microsatellite with phenotypic variation and estimated breeding values of growth traits in Canchim cattle. Animal Genetics, 39(5), 480–485. https://doi.org/10.1111/j.1365-2052.2008.01755.x
Bayram, B., Yanar, M., & Akbulut, Ö. (2004). Relationships among richards growth curve parameters, reproductive and milk production traits in brown swiss cattle sag feisfcfoh. Journal of Applied Animal Research, 26(1), 29–32. https://doi.org/10.1080/09712119.2004.9706500
Bedoya, G., Carvajal, L. G., Moreno, F. L., Davies, S., Derr, J., Ossa, J., y Ruiz, A. (2001). Estructura molecular y poblacional del ganado criollo Colombiano (GCC). Revista Colombiana de Ciencias Pecuarias, 14(2), 109–120. https://doi.org/10.17533/udea.rccp
Brody, S. (1945). Bioenergetics and growth with special reference to the efficiency in domestic animals. Hafner Publishing Company, INC. 1033 p. https://onesearch.library.rice.edu
Caivio‐Nasner, S., López‐Herrera, A., González‐Herrera, L. G., & Rincón, J. C. (2021). Diversity analysis, runs of homozygosity and genomic inbreeding reveal recent selection in Blanco Orejinegro cattle. Journal of Animal Breeding and Genetics, 138(5), 613–627. https://doi.org/10.1111/jbg.12549
Cañas, J. J., Ramírez, J., Arboleda, O., Ochoa, J., Vergara, O., y Cerón, M. (2008). Estimación de parámetros genéticos para peso al destete en ganado blanco orejinegro (BON) en el noroccidente colombiano. Revista MVZ Córdoba, 13(1), 1138–1145. https://doi.org/10.21897/RMVZ.405
Cardona, S. J. C., Álvarez, J. D. C., Sarmento, J. L. R., Herrera, L. G. G., y Cadavid, H. C. (2015). Associação de SNPs nos genes para κ-caseína e β-lactoglobulina com curvas de lactação em cabras leiteiras. Pesquisa Agropecuaria Brasileira, 50(3), 224–232. https://doi.org/10.1590/S0100-204X2015000300006
Castrelln, V. V., Vera, W. A., Bracamonte, M. P., Rincn, A. M. S., Montoya, H. M., & De la Rosa Reyna, X. F. (2010). Polymorphisms in the IGF1 gene and their effect on growth traits in Mexican beef cattle. Genetics and Molecular Research, 9(2), 875–883. https://doi.org/10.4238/vol9-2gmr745
Coelho, J. G., Barbosa, P. F., Tonhati, H., & Freitas, M. A. R. de. (2009). Análise das relações da curva de crescimento e eficiência produtiva de vacas da raça Holandesa. Revista Brasileira de Zootecnia, 38(12), 2346–2353. https://doi.org/10.1590/S1516-35982009001200008
Crispim, A. C., Kelly, M. J., Guimarães, S. E. F., e Silva, F. F., Fortes, M. R. S., Wenceslau, R. R., & Moore, S. (2015). Multi-Trait GWAS and New Candidate Genes Annotation for Growth Curve Parameters in Brahman Cattle. PLOS ONE, 10(10), 1–19. https://doi.org/10.1371/journal.pone.0139906
Dominguez-Viveros, J., Urbina-Valenzuela, A. R., Palacios-Espinoza, A., Callejas-Juárez, N., Ortega-Gutiérrez, J. Á., Espinoza-Villavicencio, J. L., Padrón-Quintero, Y., y Rodríguez-Castro, M. (2017). Caracterización del crecimiento de bovinos cebú en pruebas de comportamiento en pastoreo. Ecosistemas y Recursos Agropecuarios, 4(11), 341–348. https://doi.org/10.19136/era.a4n11.1149
Ferraz, M. V. C., Pires, A. V., Santos, M. H., Silva, R. G., Oliveira, G. B., D. M., Polizel, D. M., Biehl, M. V., Sartori, R., & Nogueira, G. P. (2018). A combination of nutrition and genetics is able to reduce age at puberty in Nelore heifers to below 18 months. Animal, 12(3), 569–574. https://doi.org/10.1017/S1751731117002464
Gaviolli, V. R. N., Buzanskas, M. E., Cruz, V. A. R., Savegnago, R. P., Munari, D. P., Freitas, A. R., & Alencar, M. M. (2012). Genetic associations between weight at maturity and maturation rate with ages and weights at first and second calving in Canchim beef cattle. Journal of Applied Genetics, 53(3), 331–335. https://doi.org/10.1007/s13353-012-0100-6
Gompertz, B. (1825). On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life Contingencies. Philosophical Transactions ofthe Royal Society of London, 115, 513–583.
http://www.jstor.org/journals/rsl.html
Gui, L., Wang, Z., Jia, J., Zhang, C., Chen, Y., & Hou, S. (2018). IGF-1 Gen Polimorfizmi Çin Qinchuan Sığırında Büyüme Özelliklerini Etkiler. Kafkas Universitesi Veteriner Fakultesi Dergisi, 24(3), 387–392. https://doi.org/10.9775/kvfd.2017.19036
Hojjati, F., & Hossein-Zadeh, N. G. (2018). Comparison of non-linear growth models to describe the growth curve of Mehraban sheep. Journal of Applied Animal Research, 46(1), 499–504. https://doi.org/10.1080/09712119.2017.1348949
Inoue, K., Hosono, M., Oyama, H., & Hirooka, H. (2020). Genetic associations between reproductive traits for first calving and growth curve characteristics of Japanese Black cattle. Animal Science Journal, 91(1), 1–8. https://doi.org/10.1111/asj.13467
Lenth, R. V. (2016). Least-Squares Means: The R Package lsmeans. Journal of Statistical Software, 69(1), 1–33. https://doi.org/10.18637/jss.v069.i01
López-Herrera, A., Saldarriaga, O. A., Arango, A. E., Fabio, N., Olivera, M., Bedoya, G., y Ossa, J. E. (2001). Ganado Blanco Orejinegro (BON): Una alternativa para la producción en Colombia. Revista Colombiana de Ciencias Pecuarias, 14(2), 121–128. https://doi.org/10.17533/udea.rccp
Londoño-Gil, M., Rincón Flórez, J. C., Lopez-Herrera, A., y Gonzalez-Herrera, L. G. (2021). Genome-wide association study for growth traits in Blanco Orejinero (BON) cattle from Colombia. Livestock Science, 243(104366), 104366. https://doi.org/10.1016/j.livsci.2020.104366
Lusk, J. L. (2007). Association of single nucleotide polymorphisms in the leptin gene with body weight and backfat growth curve parameters for beef cattle 1. American Society of Animal Science, 85, 1865–1872. https://doi.org/10.2527/jas.2006-665
M-Rocha, J. F., Gallego, J. L., Vásquez, R. F., Pedraza, J. A., Echeverri, J., Cerón-Muñoz, M. F., y Martínez, R. (2012). Estimación de parámetros genéticos para edad al primer parto e intervalo entre partos en poblaciones bovinas de la raza Blanco Orejinegro (BON) en Colombia. Revista Colombiana de Ciencias Pecuarias, 25, 220–228. https://doi.org/10.17533/udea.rccp
Martínez, R., Vásquez, R., y Gallego, J. L. (2012). Eficiencia productiva de la raza BON en el trópico colombiano. En Corpoica (Primera ed, Vol. 1). © Corporación Colombiana de Investigación Agropecuaria, Corpoica. 215 p.
Martins, G. A., Martins Filho, R., Lima, F. de A. M., y Lôbo, R. N. B. (2000). Influência de fatores genéticos e de meio sobre o crescimento de bovinos da raça Nelore no Estado do Maranhão. Revista Brasileira de Zootecnia, 29(1), 103–107. https://doi.org/10.1590/S1516-35982000000100014
Mota, L. F. M., Lopes, F. B., Fernandes Júnior, G. A., Rosa, G. J. M., Magalhães, A. F. B., Carvalheiro, R., y Albuquerque, L. G. (2020). Genome-wide scan highlights the role of candidate genes on phenotypic plasticity for age at first calving in Nellore heifers. Scientific Reports, 10(1), 6481. https://doi.org/10.1038/s41598-020-63516-4
R Core Team. (2020). R: A Language and Environment for Statistical Computing (4.0.0). R Foundation for Statistical Computing. https://www.r-project.org
Ramírez, E., Cerón-Muñoz, M., Herrera, A. C., Vergara, O. D., Arboleda, E. M., y Restrepo, L. F. (2009). Crecimiento de hembras cruzadas en el trópico colombiano. Revista Colombiana de Ciencias Pecuarias, 22, 642–647. https://doi.org/10.17533/udea.rccp
Rincón, J., y Quintero, J. (2015). Comparación de modelos no lineales para describir el crecimiento en ganado Blanco Orejinegro (BON). Revista CES Medicina Veterinaria y Zootecnia, 10(1), 31–37. https://doi.org/10.21615/cesmvz
Rogberg-Muñoz, A., Melucci, L., Prando, A., Villegas-Castagnasso, E. E., Ripoli, M. V., Peral-García, P., Baldo, A., Añon, M. C., & Giovambattista, G. (2011). Association of bovine chromosome 5 markers with birth and weaning weight in Hereford cattle raised under extensive conditions. Livestock Science, 135(2–3), 124–130. https://doi.org/10.1016/j.livsci.2010.06.160
Rogberg-Muñoz, A., Cantet, R. J. C., Elena, M., Pedro, J., Prando, A., Nélida, A., Verónica, M., y Giovambattista, G. (2013). Longitudinal analysis of the effects of IGF1 - SnaBI genotypes on the growth curve of Angus bull calves. Livestock Science, 154(1–3), 55–59. https://doi.org/10.1016/j.livsci.2013.03.016
Saleem, A. H. (2015). Role of Leptin in Growth, Reproduction and Milk Production in Farm Animals: A Review. Advances in Animal and Veterinary Sciences, 3(5), 302–307. https://doi.org/10.14737/journal.aavs/2015/3.5.302.307
Verhulst, P. (1838). Notice sur la loi que la population pursuit dans son accroissement. Correspondance Mathématique et Physique, 10,113-121. http://www.neo-classical-physics.info/uploads/3/4/3/6/34363841/verhulst_-_law_of_population.pdf
Von Bertalanffy, L. (1938). A quantitative theory of organic growth (inquires on growth laws. Human Biology, 10(2), 181–213. https://doi.org/10.2307/41447359
Published
2022-06-21
How to Cite
Londoño-Gil, M., González-Herrera, L., López-Herrera, A., & Rincón Flórez, J. (2022). Effect of IGF-1 and LEP/ob SNPs on growth parameters of Blanco Orejinegro cattle. Revista De La Facultad De Agronomía De La Universidad Del Zulia, 39(2), e223933. Retrieved from https://produccioncientificaluz.org/index.php/agronomia/article/view/38276
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Animal Production
Copyright (c) 2022 Marisol Londoño-Gil, Luis Gabriel González-Herrera, Albeiro López-Herrera and Juan Carlos Rincón Flórez
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