TGF-β1 Expression in Osphronemus gouramy Scale Application in Rattus novergicus Tooth Socket

Chiquita Prahasanti, Anneke Paramita Adityatama, Okkinardo Arief, Okkinardo Arief


The aim of the study is to observe an enhancement of TGF-β1 expression in gourami fish-scale application in Wistar rat tooth socket. As a method, thirty-six experimental animals were randomly divided into 4 groups as 7 and 14 days’ control group and 7 and 14 days’ fish-scale group. TGF-β1 expression was analyzed under immunohistochemistry on days 7 and 14. Results: Statistic test one-way ANOVA with a significant number 0.000 (p < 0,05) and Tukey HSD multiple comparisons showed a significant difference between groups. In conclusion, a Fish-scale scaffold derived from gourami can enhance the expression of TGF-β1

Palabras clave

Gouramy, Fish-scale, Scaffold, TGF- β1.

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Universidad del Zulia /Venezuela/ opción/ /ISSN: 1012-1587 / e-ISSN: 2477-9385

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