Antibiotic and Antifungi activity of B. cepacia originating of nosocomial environmental. Independent Service University Hospital “Antonio Patricio Alcalá”. Cumaná, Venezuela

  • Yasmina Araque Postgraduate in Fundamental Medical Sciences University of the Andes. Venezuela. Department of Bioanalysis, Universidad de Oriente- Nucleo de Sucre. Venezuela.
  • Luzmila Albarado Department of Bioanalysis, Universidad de Oriente- Nucleo de Sucre. Venezuela.
  • Sara Centeno Department of Bioanalysis, Universidad de Oriente- Nucleo de Sucre. Venezuela.
  • Vidal Rodríguez Lemoine Institute of Experimental Biology. Central University of Venezuela. Venezuelan Center for Microorganism Collections-CVCM.
  • Juana Vitelli Flores Venezuelan Center for Microorganism Collections-CVCM.
Keywords: Burkholderia cepacia, antibiotic, antifungi

Abstract

Burkholderia cepacia is a Gram-negative and non-fermenter bacilli, known as a causal agent of opportunistic infections, as well as producer of compounds with antimicrobial activities. In the present study, the antagonism of nine (9) nosocomial isolates of B. cepacia against filamentous fungi, yeast and bacteria from hospital environments was evaluated. The antibacterial and antifungal detection was determined according to the double layer technique and cylindrical sections in agar, respectively. Four B. cepacia isolates (CVCM: 626, 1328, 1331 and 1332) inhibited the different bacterial species analyzed. B. cepacia CVCM 1332 inhibited five (5) of the six (6) indicators of bacterial species, with inhibition halos between 11 and 22 mm, with the exception of P. fluoresecens. Three (3) B. cepacia isolates did not show antibacterial activity. Two B. cepacia isolates inhibited the studied fungi (Fusarium solani, Penicillium citrinum, Penicillium frequentans, Aspergillus niger, Aspergillus ochoraceus, Penicillium echinulatum, Candida tropicalis, Candida famata). The species CVCM 626, 1328 and 1331 showed both antibacterial and antifungal activities. The antagonism of nosocomial B. cepacia isolates against bacteria and fungi from hospital environments was demonstrated, representing an important factor in the colonization of critical areas, facilitating the appearance of infectious symptoms in hospitalized patients.

Published
2007-12-24
How to Cite
1.
Araque Y, Albarado L, Centeno S, Rodríguez Lemoine V, Vitelli Flores J. Antibiotic and Antifungi activity of B. cepacia originating of nosocomial environmental. Independent Service University Hospital “Antonio Patricio Alcalá”. Cumaná, Venezuela. Kasmera [Internet]. 2007Dec.24 [cited 2024Jul.18];35(2):107-1. Available from: https://produccioncientificaluz.org/index.php/kasmera/article/view/4789
Issue
Vol. 35 No. 2 (2007)
Section
Original Articles

Copyright (c) 2007 Yasmina Araque, Luzmila Albarado, Sara Centeno, Vidal Rodríguez Lemoine, Juana Vitelli Flores

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Kasmera journal is registered under a Creative Commons an Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0), available at: https://creativecommons.org/licenses/by-nc-sa/4.0/deed.en; which guarantees the freedom to share-copy and redistribute the material in any medium or format and adapt-remix, transform and build from the material, provided that the name of the authors, the Department of Infectious and Tropical Diseases, Zulia´s University and Kasmera Journal, you must also provide a link to the original document and indicate if changes have been made.

The Department of Infectious and Tropical Diseases, University of Zulia and Kasmera Journal do not retain the rights to published manuscript and the contents are the sole responsibility of the authors, who retain their moral, intellectual, privacy and publicity rights. The guarantee on the intervention of the manuscript (revision, correction of style, translation, layout) and its subsequent dissemination is granted through a license of use and not through a transfer of rights, which represents the Kasmera Journal and Department Infectious Diseases, University of Zulia are exempt from any liability that may arise from ethical misconduct by the authors.

Kasmera is considered a green SHERPA/RoMEO journal, that is, it allows self-archiving of both the pre-print (draft of a manuscript) and the post-print (the corrected and peer-reviewed version) and even the final version (layout as it will be published in the journal) both in personal repositories and in institutional and databases.