Immunological Role of Lung Epithelial Cells

  • Bruno Rivas-Santiago National Institute of Respiratory Diseases. Department of Research in Microbiology
  • Patricia Vieyra-Reyes Institute of Cellular Physiology. National Autonomous University of Mexico.
  • Carlos Fernández de Larrea Vargas Hospital of Caracas, Central University of Venezuela.
  • Zaida Araujo Laboratory of Infectious Diseases, Institute of Biomedicine, Central University of Venezuela.
Keywords: Epithelial cells, antimicrobial peptides, defensins, innate immunity

Abstract

The respiratory tract is one of the main apparatus which is in daily contact with a wide variety of microorganisms, however, only on a few occasions is infection establish because of its innate immune response. Respiratory tract epithelial cells play a very important role in avoiding infectious agent colonization of the lungs, since this kind of cell can recognize microbial molecules through very specialized receptors such as Toll-like. Moreover these cells posses a broad variety of molecules which are related to local immunity. Respiratory tract epithelial cells are capable of producing several chemokines, antimicrobial peptides and other pro-inflammatory molecules.

Published
2006-06-15
How to Cite
1.
Rivas-Santiago B, Vieyra-Reyes P, Fernández de Larrea C, Araujo Z. Immunological Role of Lung Epithelial Cells. Kasmera [Internet]. 2006Jun.15 [cited 2024Jul.17];34(1):61-8. Available from: https://produccioncientificaluz.org/index.php/kasmera/article/view/4770
Issue
Vol. 34 No. 1 (2006)
Section
Narrative Review

Copyright (c) 2006 Bruno Rivas-Santiago, Patricia Vieyra-Reyes, Carlos Fernández de Larrea, Zaida Araujo

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