Antimicrobial Susceptibility and b-Lactamase Production in Strains of Neisseria gonorrhoeae Isolated in Patients from the University Hospital “Dr. Manuel Núñez Tovar”, Monagas State-Venezuela

  • J Lanz University Hospital "Dr. Manuel Nuñez Tovar ”
  • H De Freitas Chair of Pathophysiology. Oriente University, Sucre Nucleus.
  • J Betancourt Chair of Clinical Bacteriology, School of Sciences, Department of Bioanalysis, Oriente University.
  • N Núñez University Hospital "Dr. Manuel Nuñez Tovar ”
  • W Velásquez Chair of Pathophysiology. Oriente University, Sucre Nucleus.
Keywords: Neisseria gonorrhoeae, susceptibility, beta-lactamase, antimicrobial, resistance, gonorrhoea

Abstract

In order to determine the patterns of antimicrobial susceptibility and beta-lactamase production, 60 patients with sexually transmitted diseases were studied from the University Hospital “Dr. Manuel Nuñez Tovar” jurisdiction in Monagas State. Thirty-five N. gonorrhoeae strains (58,30%) were isolated, and they were grouped according to antimicrobial susceptibility and beta-lactamase production. A high resistance rate to penicillin (94.24%) and to tetracycline (97.14%) was detected. Out of the 33 N. gonorrhoeae strains resistant to penicillin, 15 (45.45%) did not produce beta-lactamase. On the other hand, in vitro sensitivity of N. gonorrhoeae to cefepime, cefoxitin and ceftriaxone was 97.14%, 94.29%, and 80.50%, respectively . In relation to the susceptibility to ofloxacin, it was found that 97,14% of the strains of N. gonorrhoeae showed sensitivity a this antimicrobial. treatment.

Author Biographies

J Lanz, University Hospital "Dr. Manuel Nuñez Tovar ”
Licenciados en Bioanálisis
N Núñez, University Hospital "Dr. Manuel Nuñez Tovar ”
Licenciados en Bioanálisis.
Published
2004-05-28
How to Cite
1.
Lanz J, De Freitas H, Betancourt J, Núñez N, Velásquez W. Antimicrobial Susceptibility and b-Lactamase Production in Strains of Neisseria gonorrhoeae Isolated in Patients from the University Hospital “Dr. Manuel Núñez Tovar”, Monagas State-Venezuela. Kasmera [Internet]. 2004May28 [cited 2024Nov.25];32(1):27-5. Available from: https://produccioncientificaluz.org/index.php/kasmera/article/view/4734
Issue
Vol. 32 No. 1 (2004)
Section
Original Articles

Copyright (c) 2004 J Lanz, H De Freitas, J Betancourt, N Núñez, W Velásquez

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