D-dimer levels in patients with COVID-19
Abstract
High levels of D-dimer have been associated with respiratory failure, it is a marker of thrombotic events, one of the most common complications of COVID-19, The objective of this study is to evaluate D-dimer levels in patients with COVID-19. A total of 344 patients who attended the Clinical Laboratory, between September 2020 and August 2021, highly suggestive symptoms of infection in the last 5 days or less were included. Each patient was diagnosed with SARS-CoV-2 by RT-PCR and D-dimer determination. The positivity for SARS-CoV-2 in the population evaluated with the RT-PCR test was 63.37%. 81.65% of SARS-CoV-2 positive patients had plasma concentrations from > 250 ng/mL to values of >2000 ng/mL, considered positive D-dimer with a significant difference of p< 0.05 (0.000). The predominant symptom was cough in infected patients with high levels of D-dimer, with a p< 0.05 (0.016). It is concluded that SARS-CoV-2 positive patients had high plasma levels of D-dimer, which shows that, during infection by this virus, plasma levels of this biomarker increase and that it serves as a marker of severity and mortality in COVID-19 patients
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