Multiresistant Citrobacter freundii as an etiological agent of urinary tract infection

  • Carmen Ullauri-González Microbiology, Clinical Laboratory Career. Nacional University of Loja. Ecuador http://orcid.org/0000-0002-8555-7996
  • Sandra Freire-Cuesta Patology, Clinical Laboratory Career. Nacional University of Loja. Ecuador
Keywords: drug resistance microbial, bacteriuria, Citrobacter freundii

Abstract

Citrobacter freundii, sometimes it can act as opportunistic pathogen, a case of this isolated microorganism is presented as an etiological agent of urinary tract infection, in a patient with chronic obstructive pulmonary disease. The isolate was multiresistant to gentamicin, amikacin, trimetoprim sulfamethoxazole, ciprofloxacin, ceftriaxone, ceftazidime, cefepime, imipenem, meropenem and doripenem and it was susceptible to tigecycline and colistin, the molecular analysis showed the presence of the blaKPC gene.

References

Procop G, Church D, Hall G, Janda W, Koneman E, Schreckenberger P, et al. Koneman Diagnóstico Microbiológico. Texto y Atlas. 7 Ed. Mendoza C, Karen E, editores. Barcelona: Kluwer, Wolters; 2018. p 267-269.

Brooks G, Carroll K, Butel J, Morse S, Mietzner T, Jawets M. Jawetz, Melnick y Adelberg. Microbiología Médica. 25 Ed. Mexico DF: McGrawHill; 2010. p 213-216.

Forbes B, Sahm D, Weissfeld A. Bailey & Scott Diagnóstico Microbiológico. 12 Ed. Buenos Aires: Editorial Médica Panamericana; 2009. p 328-330.

Vignoli R. Manual de Mecanismos de Resistencia a Antibióticos Macrólidos y Lincosaminas. 2016. p. 1-14. Disponible en: https://docplayer.es/42315500-Manual-de-mecanismos-de-resistencia-a-antibioticos.html

Zhang Y, Wang Q, Yin Y, Chen H, Jin L, Gu B, et al. Epidemiology of carbapenem-resistant Enterobacteriaceae infections: Report from the China CRE Network. Antimicrob Agents Chemother. 2018;62(2):e01882-17. Disponible en: https://aac.asm.org/content/62/2/e01882-17

Leski TA, Taitt CR, Bangura U, Ansumana R, Stenger DA, Wang Z, et al. Finished Genome Sequence of the Highly Multidrug-Resistant Human Urine Isolate Citrobacter freundii Strain SL151. Genome Announc. 2016;4(6):e01225-16. Disponible en: http://genomea.asm.org/lookup/doi/10.1128/genomeA. 01225-16

Gupta N, Yadav A, Choudhary U, Arora DR. Citrobacter bacteremia in a tertiary care hospital. Scand J Infect Dis. 2003;35(10):765-8. Disponible en: https://doi.org/10.1080/00365540310016376

Organización Mundial de la Salud. Enfermedad pulmonar obstructiva crónica (EPOC). WHO. World Health Organization; 2013 [citado 17 de diciembre de 2018]. Disponible en: https://www.who.int/respiratory/copd/es/

Wu W, Espedido B, Feng Y, Zong Z. Citrobacter freundii carrying blaKPC-2and blaNDM-1: Characterization by whole genome sequencing. Sci Rep. 2016;6:30670. Disponible en: https://doi.org/10.1038/srep 30670

Bueno Sancho J, Seral García CP, Castillo García FJ. Epidemiología molecular de enterobacterias productoras de carbapenemasas. Trabajo fin de master iniciación a la investigación En medicina. Universidad de Zaragoza; 2015. Disponible en: https://zaguan.unizar.es/record/47451/files/TAZ-TFM-2015-161.pdf

Reilly J, Silverman E, Shapiro S. Enfermedad pulmonar obstructiva crónica. En: Longo D, Fauci A, Kasper D, Stephen H, Lameson JL, Loscalzo J, editores. Harrison Principios de Medicina Interna. 18 Ed. Volumen 2. Mexico D.F. McGraw-Hill Interamericana Editores, S.A. de C.V.; 2012. p 2151-2.

CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 28th Ed. Clinical and Laboratory Standars Institute–CLSI. Wayne PA. 2018 p 296.

Kalpana G, Trautner B. Infecciones de vías urinarias, pielonefritis y prostatitis. En: Longo D, Fauci A, Kasper D, Stephen H, Lameson JL, Loscalzo J, editores. Harrison Principios de Medicina Interna. 18 Ed. Infecciones de vías urinarias, pielonefritis y prostatitis: McGraw-Hill Interamericana Editores, S.A. de C.V.; 2012. p 2387-8.

Organización Mundial de la Salud. Enfermedades respiratorias crónicas. WHO. 2016 [citado 14 de agosto de 2018]. Disponible en: https://www.who.int/respiratory/es/

Erkens-Hulshof S, Virginia-Cova L, van Dijk W, Severin J, Woodford N, Melchers W, et al. The occurrence of Enterobacteriaceae producing KPC carbapenemases in a general hospital in Curacao. Antimicrob Resist Infect Control. 2014;3(1):24. Disponible en: https://doi.org/10.1186/2047-2994-3-24

Lorenzoni VV, Silva D da C, Rampelotto RF, Brites PC, Villa B, Hörner R. Evaluation of carbapenem-resistant Enterobacteriaceae in a tertiary-level reference hospital in Rio Grande do Sul, Brazil. Rev Soc Bras Med Trop. 2017;50(5):685-8. Disponible en: http://www.scielo.br/scielo .php?script=sci_arttext&pid=S0037-86822017000500685&lng= en&tlng=en

Yang L, Li P, Liang B, Hu X, Li J, Xie J, et al. Multidrug-resistant Citrobacter freundii ST139 co-producing NDM-1 and CMY-152 from China. Sci Rep. 2018;8(1):10653. DOI: https://doi.org/10.1038/s41598-018-28879-9

Venditti C, Fortini D, Villa L, Vulcano A, D’Arezzo S, Capone A, et al. Circulation of blaKPC-3-carrying IncX3 plasmids among Citrobacter freundii isolates in an Italian Hospital. Antimicrob Agents Chemother. 2017;61(8):e00505-17. Disponible en: https://aac.asm.org/content/61/8/e00505-17

Gaibani P, Ambretti S, Farruggia P, Bua G, Berlingeri A, Tamburini MV, et al. Outbreak Of Citrobacter freundii carrying Vim-1 in an italian hospital, identified during the carbapenemases screening actions, 2012. Int J Infect Dis. 2013;17(9):e714-7. DOI: https://doi.org/10.1016/j.ijid.2013.02.007

Gross C, Allen-Bridson K, Anttila A, Brooks JE, Hebden JN, Leaptrot D, et al. Health Care-Associated Infections Studies Project Case #1: A 2015 American Journal of Infection Control and National Healthcare Safety Network data quality collaboration. Am J Infect Control. 2015;43(9):987-8. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/ 26209338

Mahmoud A. M, Tarig M.S. A, Osama M. S, Mariam M. A. Prevalence and antimicrobial resistance pattern of bacterial strains isolated from patients with urinary tract infection in Messalata Central Hospital, Libya. Asian Pac J Trop Med. 2016;9(8):771-6. Disponible en: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L613140529%0Ahttp://dx.doi.org/10.1016/j.apjtm.2016.06.011%0Ahttp://iacs.c17.net/openurl?sid=EMBASE&issn=19957645&id=doi:10.1016%2Fj.apjtm.2016.06.011&atitle=Prevalence+and+antimicro

Hazen TH, Mettus RT, McElheny CL, Bowler SL, Doi Y, Rasko DA. Draft Genome Sequences of blaKPC-Containing Enterobacter aerogenes, Citrobacter freundii, and Citrobacter koseri Strains. Microbiol Resour Announc. 2018;6(8). Disponible en: https://mra.asm.org/content /6/8/e00035-18

Published
2019-06-11
How to Cite
1.
Ullauri-González C, Freire-Cuesta S. Multiresistant Citrobacter freundii as an etiological agent of urinary tract infection. Kasmera [Internet]. 2019Jun.11 [cited 2025May29];47(1):9-13. Available from: https://produccioncientificaluz.org/index.php/kasmera/article/view/24671
Issue
Vol. 47 No. 1 (2019)
Section
Clinical Case

Copyright (c) 2019 Carmen Ullauri-González, Sandra Freire-Cuesta

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