Análisis comparativo de los niveles de proteína sanguínea y progesterona en cabras cruzadas y cabras de Damasco en la región árida de Argelia

• Zahra Rouabah Batna1 University, Institute of Veterinary Sciences and Agronomic Sciences, Department of Veterinary Sciences, Laboratory of Environment, Health and Animal Production (ESPA). Batna, Algeria. https://orcid.org/0000-0003-1766-5239
• Lilia Belkacem Batna1 University, Institute of Veterinary Sciences and Agronomic Sciences, Department of Veterinary Sciences, Laboratory of Environment, Health and Animal Production (ESPA). Batna, Algeria. https://orcid.org/0000-0002-5994-6672
• Manel Merradi Batna 2 University; Department of Microbiology and Biochemistry, Faculty of Natural and Life Sciences. Batna, 05078, Algeria. https://orcid.org/0009-0001-2138-4272
• Nouzha Heleili Batna1 University, Institute of Veterinary Sciences and Agronomic Sciences, Department of Veterinary Sciences, Laboratory of Environment, Health and Animal Production (ESPA). Batna, Algeria. https://orcid.org/0000-0002-5106-6961
• Yacine Kasmi Batna1 University, Institute of Veterinary Sciences and Agronomic Sciences, Department of Veterinary Sciences, Laboratory of Environment, Health and Animal Production (ESPA). Batna, Algeria. https://orcid.org/0009-0009-8570-5416

DOI: https://doi.org/10.52973/rcfcv-e363917

Palabras clave: Mestizo, Damasco, cabra, progesterona, perfil proteico

Resumen

El estudio evaluó la influencia de la raza y el estado reproductivo sobre los perfiles de progesterona y proteínas sanguíneas en una muestra de diez cabras de entre 1,5 y 3 años. Las cabras fueron categorizadas en dos grupos iguales: la raza Damasco y un grupomestizo (Damasco x Arbia). Todos los sujetos fueron sometidos a sincronización de estros seguida de monta natural. Se recogieron muestras de sangre en varias etapas: antes de la introducción de esponjas intravaginales, al principio de la gestación (30 días después del monta), a mitad de la gestación (90 días), al final de la preñez (130 días) y en el periodo posparto a los 30 días. Los resultados revelaron un impacto significativo (P < 0,01; P < 0.001) de la etapa productiva en los niveles de progesterona en ambos grupos, junto con niveles notables de albúmina en las cabras de Damasco (P < 0,05; P < 0,01). Sin embargo, las concentraciones de proteínas totales y globulina no mostraron variaciones significativas a lo largo de las fases fisiológicas en ninguno de los grupos. Se detectaron efectos específicos relacionados con la raza en el principio y medio de la preñez para la progesterona, y en el principio de la gestación y la lactancia para los niveles de proteína total y para la globulina durante la lactancia. Los cambios en los perfiles de progesterona y proteínas en ambos grupos sugieren adaptaciones fisiológicas en las cabras para compensar las mayores demandas de la gestación y lactancia en el entorno árido de Argelia.

Citas

Godber OF, Laroussi BF, Chentouf M, Wall R. Intensification of Mediterranean goat production systems: a case study in northern Morocco. Agriculture. [Internet]. 2016; 6(2):16. doi: https://doi.org/q95v DOI: https://doi.org/10.3390/agriculture6020016

Mouhous A, Djellal F, Guermah H, Kadi SA. Determinants of goat meat consumption in the Tizi-Ouzou region of Algeria. Viandes Prod. Carnés. [Internet]. 2021 [cited 12 Dec 2025]; VPC:2021-3732. Available in: https://goo.su/l7xw7FB

Chekikene AH, Souames S, Meklati F, Idres T, Benhenia K, Lamara A. Les chèvres locales algériennes: Etat des lieux de leur élevage et de leur caractérisation morphogénétique. Livest. Res. Rural Dev. [Internet]. 2021 [Accessed 27 Oct 2024], 33(49:59. Available in: https://goo.su/n20ITrf

Güney O, Torun O, Özuyanık O, Darcan N. Milk production, reproductive and growth performances of Damascus goats under northern Cyprus conditions. Small Rumin. Res. [Internet]. 2006; 65(1-2):176-179. doi: https://doi.org/b263jg DOI: https://doi.org/10.1016/j.smallrumres.2005.07.026

Mavrogenis AP, Antoniades NY, Hooper RW. The Damascus (Shami) goat of Cyprus. Anim. Genet. Resour. Inf. [Internet]. 2006; 38:57–65. doi: https://doi.org/ctjgzk DOI: https://doi.org/10.1017/S1014233900002054

Chakhma A, Khaldoun-Benabbas M, Charallah-Cherif S, Kassouri S, Khammar F, Amirat Z. Annual changes in plasma progesterone and estradiol-17β concentrations compared to pituitary-adrenal axis activity in the female goat under arid environment. Biol. Rhythm Res. [Internet]. 2021; 52(9):1394-1411. doi: https://doi.org/q95w DOI: https://doi.org/10.1080/09291016.2019.1630920

Hussain SO. Serum progesterone analysis for monitoring estrus, pregnancy and parturition in Shami goats. AL- Qadisiya J. Vet. Med. Sci. [Internet]. 2015 [cited 16 Jan 2026]; 14(2):69–73. Available in: https://goo.su/shWYI1i

Talebi J, Moghaddam A , Souri M, Mirmahmoudi R. Steroid hormone profile of Markhozdoes (Iranian Angora) throughout estrous cycle and gestation period. Trop. Anim. Health Prod. [Internet]. 2012; 44(2):355–360. doi: https://doi.org/csnsmb DOI: https://doi.org/10.1007/s11250-011-0029-5

El-Tarabany A A , Atta MA , El-TarabanyMS. Impact of breeding season on hormonal profile and some biochemical parameters at different stages of pregnancy in Baladi goats. Biol. Rhythm Res. [Internet]. 2020; 51(4):552–559. doi: https://doi.org/g8m4j8 DOI: https://doi.org/10.1080/09291016.2018.1543637

Sumaryadi MY, Manalu W. Prediction of litter size based on hormone and blood metabolite concentrations during pregnancy in Javanese thin-tail ewes. Asian-Aus. J. Anim. Sci. [Internet]. 1999; 12(5):682–688. doi: https://doi.org/q95x DOI: https://doi.org/10.5713/ajas.1999.682

Salve RR, Ingole SD, Nagvekar AS, Bharucha SV, Dagli, NR Pregnancy-associated protein and progesterone concentrations during early pregnancy in Sirohi goats. Small Rumin. Res. [Internet]. 2016; 141:45–47. doi: https://doi.org/f82nrw DOI: https://doi.org/10.1016/j.smallrumres.2016.07.003

Kawu M, Eduvie L, Lakpini C, Ayo J. Peripheral serum progesterone profile in multiparous Nigerian Red Sokoto goats between day one and 30 postpartum. Vet. Arhiv. [Internet]. 2007 [cited 19 Dec 2025]; 77(6): 543-550. Available in: https://goo.su/CTG9a

Charallah S, Amirat Z, Sulon J, Khammar F, Beckers JF. Pregnancy‐Associated Glycoprotein and Progesterone Concentrations during Pregnancy Failure in Bedouin Goats from the Southwest of Algeria. Reprod. Domest. Anim. [Internet]. 2010; 45(6):e231-e238. doi: https://doi.org/d3jzss DOI: https://doi.org/10.1111/j.1439-0531.2009.01511.x

B a l i kc i E , Yi l d i z A , G ü rd o ga n F. B l o o d m e t a b o l i te concentrations during pregnancy and postpartum in Akkaraman ewes. Small Rumin. Res. [Internet]. 2007; 67:247–251. doi: https://doi.org/b2b3fc DOI: https://doi.org/10.1016/j.smallrumres.2005.10.011

Radin, L Šek-Vugrovečki A, Pejaković-Hlede J, Vince S, LjubičićI,Šimpraga M. Blood metabolites of extensively reared Croatian multicoloured goats during early lactation and early gravidity. Vet. Arhiv. [Internet]. 2017; 87(3):273–280. doi: https://doi.org/q95z DOI: https://doi.org/10.24099/vet.arhiv.151223

Mmbeng wa VM, Gundidza BM, Gr e yling JPC, Fair MD, Schwalbach LMJ, Du-Toit JEJ, Samie A. Serum progesterone as an indicator of cyclic activity in post- partum goat does. S. Afr. J. Anim. Sci. [Internet]. 2009; [Accessed 22 Oct 2024]; 39(sup-1):306-311. Available in: https://goo.su/K5RsHS DOI: https://doi.org/10.4314/sajas.v39i1.61232

Belkacem L, Rouabah Z, Allaoui A, Bachtarzi K, Belkadi S, Safsaf B, Tlidjane M. Breed and reproductive status effects on some blood parameters in dryland goats (Algeria). Agric. Sci. Digest. [Internet]. 2025; 45(1):173–177. doi: https://doi.org/q952 DOI: https://doi.org/10.18805/ag.DF-617

Taklan AKH, Alwan AF, Nada SM. Induce estrus with ultrasonography examination and progesterone hormone assay for pregnancy diagnosis in Iraqi goats. Iraqi J. Vet. Med. [Internet]. 2017; 40(2):89–93. doi: https://doi.org/q953 DOI: https://doi.org/10.30539/iraqijvm.v40i2.118

Jarrell VL, Dziuk PJ. Effect of number of corpora lutea and fetuses on progesterone concentrations in goat blood. J. Anim. Sci. [Internet]. 1991; 69(2):770–773. doi: https://doi.org/q954 DOI: https://doi.org/10.2527/1991.692770x

Sousa NM, Garbayo JM, Figueiredo JR, Sulon J, Gonçalves PBD, Beckers JF. Pregnancy-associated glycoprotein and progesterone profiles during pregnancy and postpartum in native goats from the north-east of Brazil. Small Rumin. Res. [Internet].1999; 32(2):137–147. doi: https://doi.org/b89gjf DOI: https://doi.org/10.1016/S0921-4488(98)00171-0

Kouri A, Charallah S, Kouri F, Amirat Z, Khammar F. Reproductive performance and abortion etiologies of native Bedouin goats in arid zones of Algeria. Livest. Res. Rural Dev. [Internet]. 2018 [Accessed 22 Oct 2025]; 30(7):127. Available in: https://goo.su/pwwQZ

Gaafar KM, Gabr MK, Teleb DF. Hormonal profile during the estrous cycle and gestation in Damascus goats. Small Rumin. Res. [Internet]. 2005; 57(1):85–93. doi: https://doi.org/fj7k28 DOI: https://doi.org/10.1016/j.smallrumres.2004.07.009

Abd El-Hamid IS, Ibrahim NH, Farrag B, Younis FE, Wahba IA. Reproductive and productive efficiency of Damascus and Baladi goats under Egyptian arid conditions. Res. J. Anim. Vet. Sci. [Internet]. 2017 [cited 11 Jan 2026]; 9(1):6–14. Available in: https://goo.su/lZNNHGr

Al-Rukibat R, Ismail Z , Al-Zghoul MB, Hananeh W. Establishment of reference intervals of selected blood biochemical parameters in Shami goats. Vet. Clin. Pathol. [Internet]. 2020; 49(4):665–668. doi: https://doi.org/q956 DOI: https://doi.org/10.1111/vcp.12903

Abdul-Rahaman YT, Humid AO, Al-Dulaimi HSH. Effect of pregnant and non-pregnant on haematological and biochemical parameters of Qatari goats in Iraq. Indian J. Public Health Res. Dev. [Internet]. 2019; 10(10):2743– 2748. doi: https://doi.org/q957 DOI: https://doi.org/10.5958/0976-5506.2019.03155.3

Allaoua SA, Mahdi D, Zerari A, Rouar S. Establishment of blood chemistry reference intervals for Arbia goats, including values in phases of reproduction. Comp. Clin. Path. [Internet]. 2021; 30(1):493–502. doi: https://doi.org/q958 DOI: https://doi.org/10.1007/s00580-021-03243-y

Kumar A, Pattanaik AK, Baliyan S, Dutta N, Jadhav SE. Nutritional and haemato-biochemical modulation in dairy goats during mid-pregnancy. Indian J. Anim. Sci. [Internet]. 2018; 88(8):899–904. doi: https://doi.org/q959 DOI: https://doi.org/10.56093/ijans.v88i8.82914

Cepeda -Palacios R, Fuent e - Góme z MG, Ramír e z- Orduña JM, García-Álvarez A, Llinas-Cervantes X, Angulo C. Effects of pregnancy and post-kidding stages on haematochemical parameters in cross-bred goats. J. Appl. Anim. Res. [Internet]. 2018; 46(1):269–273. doi: https://doi.org/q96b DOI: https://doi.org/10.1080/09712119.2017.1295970

Jimoh AO, Ojo OA, Ihejirika UDG. Metabolic and oxidative status of West African dwarf does at different reproductive stages in southwest Nigeria. Bull. Natl. Res. Cent. [Internet]. 2019; 43:190. doi: https://doi.org/q96d DOI: https://doi.org/10.1186/s42269-019-0223-6

Chilliard Y. Metabolic adaptations and nutrient partitioning in the lactating animal. In: Martinet J, Houdebine LM, Head HH, eds.. Biology of lactation. INRA. France. 1999 [cited 11 Jan 2026]. p. 503–552. Available in: https://goo.su/h6FUJYX

Akkaya F, Senturk S, Mecitoğlu Z, Kasap S, Ertunc S, Kandemir C. Evaluation of metabolic profiles of Saanen goats in the transition period. J. Hellenic Vet. Med. Soc. [Internet]. 2020; 71(2):2127–2134. doi: https://doi.org/q96f DOI: https://doi.org/10.12681/jhvms.23637

Bamerny AO, Barwary MS, Alkass JE. Changes in some haematological and biochemical parameters in local black goats during pregnancy. Iraqi J. Agric. Sci. [Internet]. 2022; 53(2):378–384. doi: https://doi.org/q96 DOI: https://doi.org/10.36103/ijas.v53i2.1545

Berrani A, Meliani S, Bourabah A. Biochemical parameter variations with season, age, sex, parity and pregnancy in crossbred goats raised in Tiaret, Algeria. Acta Sci. Nat. [Internet]. 2021; 8(1):69–79. doi: https://doi.org/q96h DOI: https://doi.org/10.2478/asn-2021-0006

Allaoua SA, Mahdi D. Plasma biochemical and mineral parameters in Arbia goats of a semi-arid region of north- eastern Algeria during different stages of production. Vet. Arhiv. [Internet]. 2018; 88(5):643–660. doi: https://doi.org/q96j DOI: https://doi.org/10.24099/vet.arhiv.0068

Njidda AA, Hassan IT, Olatunji EA. Haematological and biochemical parameters of goats in a semi-arid environment fed on natural grazing rangeland of northern Nigeria. J. Agric. Vet. Sci. [Internet]. 2013; 3(2):1–8. doi: https://doi.org/q96k DOI: https://doi.org/10.9790/2380-0320108

Mohammed SA, Razzaque MA, Omar AE, Albert S, Al-Gallaf W. Biochemical and hematological profile of different goat breeds under intensive production systems. Afr. J. Biotech. [Internet]. 2016; 15(24):1253–1257. doi: https://doi.org/q96m DOI: https://doi.org/10.5897/AJB2016.15362

Anwar MM, Ramadan TA, Taha TA. Serum metabolites, milk yield and physiological responses during the first week after kidding in different goat breeds under subtropical conditions. J. Anim. Sci. [Internet]. 2012; 90(13):4795– 4806. doi: https://doi.org/f4pr4m DOI: https://doi.org/10.2527/jas.2012-5236

Saber M, Tayeb FM, Abdou OM, Abdel-Salam AB, Mousa SA. Effect of seasons and breeds on selected serum parameters and milk profile in clinically healthy lactating dairy goats in Egypt. Int. J. Vet. Sci. [Internet]. 2020; 9(2):244–248. doi: https://doi.org/q96p