Evaluation of hematological parameters, oxidative stress, Iron and unsaturated Iron binding capacity levels in Kangal shepherd dogs, before and after orchiectomy

• Ibrahım Yurdakul Sivas Cumhuriyet University, Faculty of Veterinary Medicine, Department of Surgery. Sivas, Türkiye
• Barıs Atalay Uslu Sivas Cumhuriyet University, Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination. Sivas, Türkiye

DOI: https://doi.org/10.52973/rcfcv-e34318

Keywords: Antioxidant, Kangal shepherd dog, iron, oxidative stress, hematology

Abstract

Gonadectomy is a widely used method in reproductive health management, and behavior disorder therapies of domestic animals. Anemia and its development, one of the complications of surgical castration, which has been done so much recently in shelter dogs and dogs kept at home, has been investigated in male Kangal shepherd dogs. In castrated male Kangal shepherd dogs was to investigate the relationship between gonadectomy and oxidant and antioxidant levels, Iron (Fe) concentrations, unsaturated iron binding capacity (UIBC) and some blood parameters (RBC, HGB, HCT, MCV, RDW, MCHC). Blood samples were taken from 20 adult Kangal dogs brought to a clinic before castration (Day 0) and on the 1st, 3rd and 7th days. Some biochemical analyzes and blood parameters were evaluated in the blood samples taken. For this purpose, serum total oxidant–antioxidant capacity (TAC–TOC), Iron (Fe) concentrations, unsaturated iron binding capacity (UIBC) and some blood parameters (RBC, HGB, HCT, MCV, RDW, MCHC) were examined. In this study, it was evaluated the relationship between gonadectomy and oxidant–antioxidant capacity and Fe metabolism at some serum parameters in male dogs. After the orchidectomy operation, a remarkable decrease in clinical and statistical blood parameters was observed. As a result of this study, in the analysis of blood parameters, a severe picture of anemia was observed. It was determined an important role in erythropoiesis, with orchidectomy. The statistical difference in blood parameters (P<0.05) was indicative of this.

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