Microcephaly and ZIKA Virus: Certainty or Presumption

  • Glenda Coromoto Velásquez Serra Universidad de Guayaquil. Facultad de Ciencias Médicas, Escuela de Medicina. Cátedra de Medicina Tropical. http://orcid.org/0000-0003-0942-2309
  • Camila Janina García Yuquilema Universidad de Guayaquil, Facultad de Ciencias Médicas, Carrera de Medicina.
  • Joselyn Meylin Galarza Cedeño Universidad de Guayaquil, Facultad de Ciencias Médicas, Carrera de Medicina.
  • Oscar Enrique Preciado Cañas Universidad Católica Santiago de Guayaquil
Palabras clave: células madre, retardo del crecimiento fetal, mutación, virus zika

Resumen

El virus Zika se ha asociado con la microcefalia desde 2015 con vínculos establecidos con la epidemia en Brasil, que afectó a varias mujeres embarazadas. El objetivo de esta investigación fue demostrar el vínculo entre el virus Zika y la microcefalia, a través del análisis de características relacionadas con el virus, teorías de cómo ingresa al organismo y las manifestaciones clínicas, que conducen a afecciones neurológicas. Esta es una investigación descriptiva y transversal. Las principales fuentes de información provienen de estudios en varias revistas médicas, que respaldan las ideas propuestas. Se describieron algunas características propias del virus, como neurotropismo, la capacidad de cruzar la barrera placentaria y producir degeneración de las células neuroprogenitoras, un complemento de las teorías mencionadas anteriormente. Asimismo, las alteraciones moleculares en la estructura del virus, lo que permite que el virus interfiera con el desarrollo cerebral del feto en mujeres embarazadas. La manifestación clínica que produce virus Zika se llama Síndrome congénito severo, que incluye manifestaciones en el recién nacido, como morfología del cráneo, anomalías cerebrales, contracturas congénitas y secuelas neurológicas. Todos los daños mostrados han sido identificados, gracias a exámenes neurológicos a recién nacidos, estudios de neuroimagen, neuropatología del cráneo y su tejido

Biografía del autor/a

Glenda Coromoto Velásquez Serra, Universidad de Guayaquil. Facultad de Ciencias Médicas, Escuela de Medicina. Cátedra de Medicina Tropical.
Dra. en Ciencias Mención Entomología Médica. Msc. en Entomología en Salud Pública. Epidemiólogo. Especialista en Gestión en Salud Pública. Docente Investigador de la Facultad de Ciencias Médicas, Carrera de Medicina, Cátedra de Medicina Tropical. Gestor de Investigación Carrera de Medicina. Director del Grupo de Investigación Enfermedades Tropicales Desatendidas del Ecuador. ETDE. Autora y Revisora en Revistas Académicas de Índole Nacional e Internacional. Consultora de Proyectos de Investigación (CDC, ORAS CONHU, USAID CARE).
Camila Janina García Yuquilema, Universidad de Guayaquil, Facultad de Ciencias Médicas, Carrera de Medicina.
Bachiller en Ciencias. Estudiante de medicina del octavo ciclo de la Universidad de Guayaquil. Co-coordinadora de grupo dengue en proyecto FCI de la Universidad de Guayaquil; Caracterización entomológica y epidemiológica de localidades priorizadas con carga de Dengue, Malaria y Chagas en el Ecuador” 2019-2021. Estudiante investigador en grupo ETDE “Enfermedades Tropicales Desatendidas en el Ecuador”.
Joselyn Meylin Galarza Cedeño, Universidad de Guayaquil, Facultad de Ciencias Médicas, Carrera de Medicina.
Bachiller en Ciencias. Estudiante de la Carrera de Medicina, Facultad de Ciencias Médicas, Universidad de Guayaquil. Coordinadora de grupo dengue en proyecto FCI de la Universidad de Guayaquil; Caracterización entomológica y epidemiológica de localidades priorizadas con carga de dengue, malaria y chagas en el Ecuador” Investigadora en el Grupo de Investigación de Enfermedades Tropicales Desatendidas del Ecuador (ETDE).
Oscar Enrique Preciado Cañas, Universidad Católica Santiago de Guayaquil
Médico Gineco-obstetra, Especialista en Salud Pública con experiencia en área de salud sexual y reproductiva durante 25 años. Docente en carreras de Enfermería y Medicina, en Universidad de Guayaquil, Universidad Católica Santiago de Guayaquil, Universidad Experimental de las Fuerzas Armadas (Venezuela). Co-autor de diversas investigaciones en el área de Salud Pública y Comunitaria. Libre ejercicio profesional.

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Publicado
2021-04-24
Cómo citar
1.
Velásquez Serra GC, García Yuquilema CJ, Galarza Cedeño JM, Preciado Cañas OE. Microcephaly and ZIKA Virus: Certainty or Presumption. Kasmera [Internet]. 24 de abril de 2021 [citado 26 de julio de 2021];49(1):e49133255. Disponible en: https://produccioncientificaluz.org/index.php/kasmera/article/view/33255
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