Clasificación histológica de los tumores neuroendocrinos pancreáticos

Histological Classification of Pancreatic Neuroendocrine Neoplasms

• Gabriel Arismendi-Morillo Universidad de Zulia. Maracaibo, Venezuela. https://orcid.org/0000-0001-8714-5613

DOI: https://doi.org/10.5281/zenodo.7516053

Keywords: Pancreatic Neuroendocrine Neoplasms, 2019-WHO Classification

Abstract

For classification of Pancreatic Neuroendocrine Neoplasms, histopathological evaluation and cell proliferation are required. Are classified as Neuroendocrine Tumors, Neuroendocrine Carcinomas and Mixed Neuroendocrine-Noneuroendocrine Neoplasia. According to cell proliferation, determined by the mitotic count and the Ki-67 index, they are classified into Grades (Grade 1, Grade 2 and Grade 3). This classification is linked to prognosis and response to therapy. The prognosis depends on the degree, in such a way that the aggressiveness of the biological behavior is proportional to the degree.

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