Toxicidad de la cihalotrina lambda sobre el hemograma los parámetros renales atenuados por el aceite esencial de Lavendula stoechas en conejo
Resumen
Entre los insecticidas piretroides utilizados en Argelia contra una amplia gama de plagas agrícolas se encuentra la lambda-cialotrina (LCT). El objetivo de este estudio fue investigar los efectos beneficiosos del aceite esencial de Lavendula stoechas sobre la hematotoxicidad y nefrotoxicidad del insecticida lambda cihalotrina en conejos (Cuniculus Lepus). Veintisiete (27) conejos locales sanos, con un peso medio de 1,8 kg, fueron divididos en tres grupos de nueve cada uno: el primer grupo considerado como control, el segundo grupo tratado con (100t mg/kg/BW) (LCT) y el tercer grupo tratado con una mezcla de (100 mg/kg/BW) (LCT) y (500 mg/kg/BW) aceite esencial de Lavandula s (LS.EO). Las dosis probadas se suministraron diariamente en la dieta durante un periodo de 4 semanas. Los análisis de sangre revelaron variaciones significativas en el hemograma entre los grupos tratados y de control. Se registró un aumento altamente significativo en el recuento de glóbulos blancos y linfocitos en el grupo tratado con LCT en comparación con el grupo de control (P<0,001), se observaron descensos altamente y muy altamente significativos en los niveles de RBC, HCT y HGB en el grupo tratado con LCT en comparación con el control (P<0,001 ; P<0,0001), obteniéndose el mismo resultado para los índices eritrocitarios. El análisis bioquímico de los parámetros renales mostró un aumento altamente y muy altamente significativo de las concentraciones de urea y creatinina respectivamente en el grupo tratado con LCT frente al control (P<0,001 ; P<0,0001). Por el contrario, la adición de aceite esencial de lavándulas mejoró las alteraciones hema- tológicas y bioquímicas anteriores.
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