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Valeriana rígida y decussata en la apoptosis de células cancerígenas 387
Vol. 63(4): 376 - 387, 2022
leriana fauriei. J Nat Med 2021;75(4):942-
948. doi:10.1007/s11418-021-01543-9.
16. Shi F, Li Y, Han R, Alan F, Ronghua W, Oli-
via N, Qin Q, Xinyi C, Li H, Yong Z. Valerian
and valeric acid inhibit growth of breast can-
cer cells possibly by mediating epigenetic
modifications. Sci Rep 2021;11(1):2519.
doi:10.1038/s41598-021-81620-x.
17. Farshori N, Saad E, Mohammad M, Musa-
rrat J, Ali A, Ahmed M. Anticancer activity
of Petroselinum sativum seed extracts on
MCF-7 human breast cancer cells. Asian Pa-
cific J Cancer Prev 2013; 14. doi:10.7314/
APJCP.2013.14.10.5719.
18. Purelink®. PureLink TM RNA Mini Kit. Cell
[Internet]. 2010;(12183020):1–4. Dispo-
nible en: https://tools.thermofisher.com/
content/sfs/manuals/purelink_rna_mini_
kit_man.pdf
19. Thermo ScientificTM. Maxima First Strand
cDNA Synthesis Kit for RT-qPCR, with
dsDNase. 2019. Disponible en: https://
www.thermofisher.com/order/catalog/
product/K1671?SID=srch-srp-K1671#/
K1671?SID=srch-srp-K1671.
20. Vaddavalli PL, Schumacher B. The p53 net-
work: cellular and systemic DNA damage
responses in cancer and aging [published
online ahead of print, 2022 Mar 25]. Trends
Genet 2022;S0168-9525(22)00037-3. doi:
10.1016/j.tig.2022.02.010
21. Ugalde M, Reza V, González-Trujano ME, Avu-
la B, Khan IA, Navarrete A. Isobolographic
analysis of the sedative interaction between
six central nervous system depressant drugs
and Valeriana edulis hydroalcoholic extract
in mice. J Pharm Pharmacol 2005;57(5):631-
639. doi:10. 1211/0022357056000.
22. Garrido J. Análisis por cromatografía líqui-
da de alta resolución de ácido valerénico o
sus derivados en extracto de hojas y raíz de
valeriana (Valeriana prionophylla Standl.)
Universidad de San Carlos de Guatemala.
USAC.2007; 38p. Disponible en: http://bi-
blioteca.usac.edu.gt/tesis/06/06_2611.pdf
23. Navarro E, Ginebra M. Desarrollo y Ca-
racterización de Materiales Biodegra-
dables para Regeneración Ósea [Inter-
net]. Catalunya; 2005 Disponible en:
https://upcommons.upc.edu/bitstream/
handle/2117/93360/05Mnt05de11.pdf?
sequence=5&isAllowed=y
24. Amiri A, Namavari M, Rashidi M, Fah-
midehkar MA, Seghatoleslam A. Inhi-
bitory effects of Cyrtopodion scabrum
extract on growth of human breast and
colorectal cancer cells. Asian Pac J Cancer
Prev 2015;16(2):565-570. doi:10.7314/
apjcp.2015.16.2.565.
25. Flores AMC, Martínez BM., Ruiz V, Re-
yes, Leyva. J. Evaluación in vitro de la
actividad citotóxica y antitumoral de
plantas medicinales en Cuetzalan del Pro-
greso, Puebla, México. Polibotánica [Inter-
net]. 2019;0(46):113–35.Disponible en:
http:www.polibotanica.mx.
26. Páez-Hernández G, Espinosa-Andrews H,
Castillo-Herrera G, Herrera-Rodríguez S.
Uso de aceites esenciales como agentes
quimiopreventivos contra el cáncer colo-
rrectal. RevSalJal 2020; 6 (3):199-205.
27. Chuaqui R, Cuello M, Emmert-Buck M.
Inactivación de genes supresores de tu-
mores en la carcinogénesis del cuello ute-
rino. Rev Med Chil 1999.];127(12):1501–
12. Disponible en: https://scielo.coni
cyt.cl/scielo.php?script=sci_arttext&
pid=S003498871999001200014&l-
ng=es&nrm=iso&tlng=es.
28. Hussain A, Sharma C, Khan S, Shah K,
Haque S. Aloe vera inhibits proliferation of
human breast and cervical cancer cells and
acts synergistically with cisplatin. Asian
Pac J Cancer Prev 2015;16(7):2939-2946.
doi:10.7314/apjcp.2015.16.7.293.
29. Kale J, Osterlund EJ, Andrews DW. BCL-
2 family proteins: changing partners in
the dance towards death. Cell Death Di-
ffer 2018;25(1):65-80. doi:10.1038/cdd.
2017.186.
30. Kakehashi A, Kato A, Ishii N, Wei M, Mo-
rimura K, Fukushima S, Wanibuchi H.
Valerian inhibits rat hepatocarcinogenesis
by activating GABA(A) receptor-mediated
signaling. PLoS One 2014; 9(11):e113610.
doi: 10.1371/journal.pone.0113610.
31. Condori M, Oviedo M. Evaluación del rfec-
to antiproliferativo y apoptótico del extrac-
to en acetato de rtilo de las hojas de An-
nona muricata (Guanábana) sobre células
cancerígenas (pc-3) y células epiteliales sa-
nas de próstata humana (HPrEC), Boston,
MA. 2016. MOSAICO. Arequipa; s.n; 2017;
19-21.