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Thymosin β4 regulates endothelial cell function through AKT pathway 305
Vol. 62(4): 295 - 306, 2021
microRNA-616-3p via X-linked inhibitor of
apoptosis protein targeting. Exp Ther Med
2021;21(6):661.
3. Jiang F, Xu XR, Li WM, Xia K, Wang LF,
Yang XC. Monotropein alleviates H2O2‑in-
duced inflammation, oxidative stress and
apoptosis via NF-κB/AP-1 signaling. Mol
Med Rep 2020;22(6):4828-4836.
4. Nie J. inhibits high glucose induced apop-
tosis in HUVEC by targeting Rab4. Biomed
Pharmaother 2020;131: p. 110662.
5. Mi L, Zhang Y, Xu Y, Zheng X, Zhang X,
Wang Z, Xue M, Jin X. HMGB1/RAGE pro-
inflammatory axis promotes vascular en-
dothelial cell apoptosis in limb ischemia/
reperfusion injury. Biomed Pharmacother.
2019; 116:109005.
6. Low T, Hu S-K, Goldstein AL. Complete
amino acid sequence of bovine thymosin
beta 4: a thymic hormone that induces ter-
minal deoxynucleotidyl transferase activity
in thymocyte populations. Proc Natl Acad
Sci 1981;78(2):1162-1166.
7. Dubé KN, Smart N. Thymosin β4 and the
vasculature: multiple roles in development,
repair and protection against disease. Ex-
pert Opin Biol Ther 2018;18(sup1):131-139.
8. Kupatt C, Horstkotte J, Vlastos GA, Pfos-
ser A, Lebherz C, Semisch M, Thalgott M,
Büttner K, Browarzyk C, Mages J. Embr-
yonic endothelial progenitor cells expres-
sing a broad range of proangiogenic and
remodeling factors enhance vascularization
and tissue recovery in acute and chronic
ischemia. The FASEB J 2005;19(11):1576-
1578.
9. Smart N, Risebro CA, Clark JE, Ehler E,
Miquerol L, Rossdeutsch A, Marber MS,
Riley PR. Thymosin β4 facilitates epicar-
dial neovascularization of the injured adult
heart. Ann N Y Acad Sci 2010;1194(1):97-
104.
10. Smart N, Risebro CA, Melville AA, Moses
K, Schwartz RJ, Chien KR, Riley PR. Thy-
mosin β4 induces adult epicardial proge-
nitor mobilization and neovascularization.
Nature 2007;445(7124):177-182.
11. Smart N, Risebro CA, Melville AA, Moses
K, Schwartz RJ, Chien KR, Riley PR. Thy-
mosin β4 is essential for coronary vessel
development and promotes neovasculariza-
tion via adult epicardium. Ann N Y Acad Sci
2007;1112(1):171-188.
12. Wyczółkowska J, Walczak-Drzewiecka A,
Wagner W, Dastych J. Thymosin β4 and thy-
mosin β4-derived peptides induce mast cell
exocytosis. Peptides 2007;28(4):752-759.
13. Sun C, Feng SB, Cao ZW, Bei JJ, Chen Q,
Xu XJ, Zhou Z, Yu ZP, Hu HY. Up-regulated
expression of matrix metalloproteinases in
endothelial cells mediates platelet micro-
vesicle-induced angiogenesis. Cell Physiol
Biochem 2017;41(6):2319-2332.
14. Qiu F, Song J, Bi X, Wang M, Zhao Y, Fu
G. Thymosin β4 promotes glucose-impaired
endothelial progenitor cell function via Akt/
endothelial nitric oxide synthesis signaling
pathway. Exp Ther Med 2018;16(4):3439-
3444.
15. Dong W, Luo B, Qiu C, Jiang X, Shen B,
Zhang L, Liu W, Zhang W. TRIM3 attenua-
tes apoptosis in Parkinson’s disease via ac-
tivating PI3K/AKT signal pathway. Aging
(Albany NY) 2020;13(1):735-749.
16. Wang Y, Lin Y, Wang L, Zhan H, Luo X,
Zeng Y, Wu W, Zhang X, Wang F. TREM2
ameliorates neuroinflammatory response
and cognitive impairment via PI3K/AKT/
FoxO3a signaling pathway in Alzheimer’s
disease mice. Aging (Albany NY)
2020;12(20):20862-20879.
17. Xu L, Chen J, Jia L, Chen X, Awaleh
Moumin F, Cai J. SLC1A3 promotes gas-
tric cancer progression via the PI3K/AKT
signalling pathway. J Cell Mol Med 2020
;24(24):14392-14404.
18. Zhu S, Liu X, Xue M, Li Y, Cai D, Wang
S, Zhang L. 20(S)-ginsenoside Rh2 induces
caspase-dependent promyelocytic leuke-
mia-retinoic acid receptor A degradation in
NB4 cells via Akt/Bax/caspase9 and TNF-α/
caspase8 signaling cascades. J Ginseng Res
2021;45(2):295-304.
19. Zhou P, Xie W, Luo Y, Lu S, Dai Z, Wang
R, Sun G, Sun X. Protective effects of total
saponins of Aralia elata (Miq.) on endothe-
lial cell injury induced by TNF-α via modu-
lation of the PI3K/Akt and NF-κB signalling
pathways. Int J Mol Sci 2018;20(1):36.
20. Rajendran P, Rengarajan T, Thangavel
J, Nishigaki Y, Sakthisekaran D, Sethi
G, Nishigaki I. The vascular endothe-