Tumores neuroendocrinos pancreáticos, ¿de qué se trata y cuándo sospechar?
Pancreatic neuroendocrine tumors, what is it and when to suspect?
Palabras clave:
tumores neuroendocrinos pancreáticos, manifestaciones clínicas, metástasis
Resumen
Los tumores neuroendocrinos pancreáticos (TNEP) son neoplasias de crecimiento lento cuya patogenia molecular no se conoce por completo. El progreso en los métodos de diagnóstico y la sospecha clínica podría ser una de las razones del aumento de la incidencia de aumento del diagnóstico de neoplasias neuroendocrinas pancreáticos en los últimos tiempos.
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Citas
Jeune F, Taibi A, Gaujoux S. Update on the surgical treatment of pancreatic neuroendocrine tumors. Scand J Surg 2020;109:42-52.
Fang JM, Shi J. A clinicopathologic and molecular update of pancreatic neuroendocrine neoplasms with a focus on the new World Health organization classification. Arch Pathol Lab Med 2019;143:1317-1326.
Mpilla GB, Philip PA, El-Rayes B, et al. Pancreatic neuroendocrine tumors: therapeutic challenges and research limitations. World J Gastroenterol 2020;26:4036-4054.
Fazio N. Personalizing multimodal treatment in patients with pancreatic neuroendocrine. Tumors. JCO Oncol Pract 2020;16:729-730.
Lee L, Ito T, Jensen RT. Prognostic and predictive factors on overall survival and surgical outcomes in pancreatic neuroendocrine tumors: recent advances and controversies. Expert Rev Anticancer Ther 2019;19:1029-1050.
Scott AT, Howe JR. Evaluation and management of neuroendocrine tumors of the pancreas. Surg Clin 2019;99:793-814.
Fraenkel M, Faggiano A, Valk GD. Epidemiology of Neuroendocrine Tumors. Front Horm Res 2015;44:1-23.
Raphael MJ, Chan DL, Law C, Singh S. Principles of diagnosis and management of neuroendocrine tumours. CMAJ 2017;189(10):E398-E404.
Janson ET, Knigge U, Dam G, Federspiel B, Grønbaek H, Stålberg P, Langer SW, Kjaer A, Arola J, Schalin-Jäntti C, Sundin A, Welin S, Thiis-Evensen E, Sorbye H. Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. Acta Oncol 2021;60(7):931-941.
Dillon JS. Workup of Gastroenteropancreatic Neuroendocrine Tumors. Surg Oncol Clin N Am 2020;29(2):165-183.
Ma Z, Cai H, Cui Y. Progress in the treatment of esophageal neuroendocrine carcinoma Tumour Biol 2017;39(6):1010428317711313.
Terada T. Small cell neuroendocrine carcinoma of the esophagus: report of 6 cases with immunohistochemical and molecular genetic analysis of KIT and PDGFRA. Int J Clin Exp Pathol 2013;6(3):485-91.
Sprague JE, Arbeláez AM. Glucose counterregulatory responses to hypoglycemia. Pediatr Endocrinol Rev 2011;9(1):463-73.
Wermers RA, Fatourechi V, Wynne AG, Kvols LK, Lloyd RV. The glucagonoma syndrome. Clinical and pathologic features in 21 patients. Medicine (Baltimore) 1996;75(2):53-63.
Stacpoole PW. The glucagonoma syndrome: clinical features, diagnosis, and treatment. Endocr Rev 1981;2(3):347-61.
Oronsky B, Ma PC, Morgensztern D, Carter CA. Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas. Neoplasia 2017;19(12):991-1002.
Verner JV, Morrison AB. Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. Am J Med 1958;25(3):374-80.
Couvelard A, Scoazec JY. Syndromes de prédisposition aux tumeurs neuroendocrines gastro-entéro-pancréatiques et thoraciques [Inherited tumor syndromes of gastroenteropancreatic and thoracic neuroendocrine neoplasms]. Ann Pathol. 2020;40(2):120-133. pág. 6
Fang JM, Shi J. A clinicopathologic and molecular update of pancreatic neuroendocrine neoplasms with a focus on the new World Health organization classification. Arch Pathol Lab Med 2019;143:1317-1326.
Mpilla GB, Philip PA, El-Rayes B, et al. Pancreatic neuroendocrine tumors: therapeutic challenges and research limitations. World J Gastroenterol 2020;26:4036-4054.
Fazio N. Personalizing multimodal treatment in patients with pancreatic neuroendocrine. Tumors. JCO Oncol Pract 2020;16:729-730.
Lee L, Ito T, Jensen RT. Prognostic and predictive factors on overall survival and surgical outcomes in pancreatic neuroendocrine tumors: recent advances and controversies. Expert Rev Anticancer Ther 2019;19:1029-1050.
Scott AT, Howe JR. Evaluation and management of neuroendocrine tumors of the pancreas. Surg Clin 2019;99:793-814.
Fraenkel M, Faggiano A, Valk GD. Epidemiology of Neuroendocrine Tumors. Front Horm Res 2015;44:1-23.
Raphael MJ, Chan DL, Law C, Singh S. Principles of diagnosis and management of neuroendocrine tumours. CMAJ 2017;189(10):E398-E404.
Janson ET, Knigge U, Dam G, Federspiel B, Grønbaek H, Stålberg P, Langer SW, Kjaer A, Arola J, Schalin-Jäntti C, Sundin A, Welin S, Thiis-Evensen E, Sorbye H. Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. Acta Oncol 2021;60(7):931-941.
Dillon JS. Workup of Gastroenteropancreatic Neuroendocrine Tumors. Surg Oncol Clin N Am 2020;29(2):165-183.
Ma Z, Cai H, Cui Y. Progress in the treatment of esophageal neuroendocrine carcinoma Tumour Biol 2017;39(6):1010428317711313.
Terada T. Small cell neuroendocrine carcinoma of the esophagus: report of 6 cases with immunohistochemical and molecular genetic analysis of KIT and PDGFRA. Int J Clin Exp Pathol 2013;6(3):485-91.
Sprague JE, Arbeláez AM. Glucose counterregulatory responses to hypoglycemia. Pediatr Endocrinol Rev 2011;9(1):463-73.
Wermers RA, Fatourechi V, Wynne AG, Kvols LK, Lloyd RV. The glucagonoma syndrome. Clinical and pathologic features in 21 patients. Medicine (Baltimore) 1996;75(2):53-63.
Stacpoole PW. The glucagonoma syndrome: clinical features, diagnosis, and treatment. Endocr Rev 1981;2(3):347-61.
Oronsky B, Ma PC, Morgensztern D, Carter CA. Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas. Neoplasia 2017;19(12):991-1002.
Verner JV, Morrison AB. Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. Am J Med 1958;25(3):374-80.
Couvelard A, Scoazec JY. Syndromes de prédisposition aux tumeurs neuroendocrines gastro-entéro-pancréatiques et thoraciques [Inherited tumor syndromes of gastroenteropancreatic and thoracic neuroendocrine neoplasms]. Ann Pathol. 2020;40(2):120-133. pág. 6
Publicado
2022-10-25
Cómo citar
Lizarzábal-García, M., & Mengual-Moreno, E. (2022). Tumores neuroendocrinos pancreáticos, ¿de qué se trata y cuándo sospechar? Pancreatic neuroendocrine tumors, what is it and when to suspect?. Revista Profesional HígadoSano, (24), 3-6. https://doi.org/10.5281/zenodo.7515867
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