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CONCLUSION
In conclusion, the antiproliferative effects as chemopreventive of
TCAE and NOD were evaluated in experimental colon cancer induced
by AOM, and it was found that both TCAE and NOD had antiproliferative
effects on PCNA and AgNOR indices. The results of this study suggest
that both TCAE and NOD were effective as chemopreventive agents and
that, compared to NOD, TCAE is one step ahead as an antiproliferative
agent in colon cancer. In addition, AgNAI, AgNCI and PCNA can be used
safely in colon cancer studies in the follow-up of carcinogenesis and
in determining the prognosis.
CONFLICT OF INTEREST
The authors declare that they have no conict of interest.
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